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pentobarbital will lower the extent or outcome of linagliptin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Use of other remedies is strongly advisable when linagliptin would be to be administered that has a CYP3A4 inducerPhenobarbital has the lowest lipid solubility, least expensive plasma binding, lowest br